ViviRen™ Live Cell Substrate

ViviRen™ Live Cell Substrate is a uniquely engineered coelenterazine that generates three- to fivefold brighter Renilla luciferase luminescence than wildtype coelenterazine. Using live cells, achieve up to 100-fold higher signal-to-noise ratios for super-sensitive quantitation of reporter gene, BRET and RNAi activity.

Cat.# E6491 is supplied as a liquid, 60mM in DMSO. Cat.# E6492 and E6495 are supplied as a lyophilized solid.

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ViviRen™ Live Cell Substrate is a uniquely engineered coelenterazine that generates three- to fivefold brighter Renilla luciferase luminescence than wildtype coelenterazine. Using live cells, achieve up to 100-fold higher signal-to-noise ratios for super-sensitive quantitation of reporter gene, BRET and RNAi activity.

Cat.# E6491 is supplied as a liquid, 60mM in DMSO. Cat.# E6492 and E6495 are supplied as a lyophilized solid.

Features - Benefits

• Three- to Fivefold Brighter Renilla Luminescence than Coelenterazine: Quantitate with confidence using miniaturized formats, low-level expression and CCD imagers.
• Low Autoluminescence: Achieve unparalleled sensitivity with up to 100-fold higher signal-to-noise ratios than coelenterazine.
• Live Cell Assay: Generate kinetic profiles for reporter gene, BRET and RNAi applications.
• Multiplex Options: Improve accuracy and precision by combining with CellTiter-Glo® and other lytic assays.

Applications

• Reporter gene analysis.
• BRET.
• RNAi.

For more information, see the Protocols & Applications Guide.

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